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<p>Basic research on the pharmacology of itch has exploded in the wake of two very influential papers that were published in Nature (2007) and Science (2009). Long overlooked as a milder form of pain, itching has rapidly gained a new appreciation in both research and clinical communities because of its complexity and its negative effects on the quality of life of the distressed patients. Like pain, not all itches are the same. Unlike pain, there are no standard drugs equivalent to aspirin and morphine. Epidemiological studies emphasize the high incidence and economic costs of itch (pruritus). It is the most prevalent symptom of a wide variety of allergic and inflammatory skin conditions (e.g., psoriasis, atopic dermatitis), is associated with several systemic diseases (e.g., chronic kidney and liver disease), and occurs in patients undergoing hemodialysis, spinal administration of opioids, and in those suffering from AIDS. The reader will learn about the multiple pathways for itch and their interactions with pain. The relationship between these closely related, yet distinct sensory phenomena, will be emphasized. Both itch and pain use several common molecules to send signals to the brain. Thus, drugs that have been, and are being, developed as analgesics may also attenuate intractable itch. This has been an exciting and very necessary turn of events since traditional H-1 receptor antagonists are ineffective in blocking the pruritus associated with kidney failure and cholestasis. The clinical chapters will provide insights into contemporary treatment regimens for pruritus in different human scenarios.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
24,309円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Pharmacology of Itch【電子書籍】
<p><b>Get practical, hands-on experience in Kubernetes securityーfrom mastering the fundamentals to implementing advanced techniques to safeguard your Kubernetes deployments against malicious threats</b></p><h2>Key Features</h2><ul><li>Understand Kubernetes security fundamentals through real-world example...
3,874円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Learning Kubernetes Security A practical guide for secure and scalable containerized environments【電子書籍】[ Raul Lapaz ]
<p>In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experience...
10,715円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア SGLT-2 Inhibitors, An Issue of Heart Failure Clinics, E-Book SGLT-2 Inhibitors, An Issue of Heart Failure Clinics, E-Book【電子書籍】
<p>Black tides of spilled oil pollute the world's coasts with depressing regularity, giving scientists ample opportunity to observe their environmental impacts and learn how to clean up and restore the affected shorelines. Miles O. Hayes has been a leader in this work for over twenty years. In this hi...
5,517円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Black Tides【電子書籍】[ Miles O. Hayes ]
<p>Diese Einf?hrung beschreibt diejenigen Eigenschaften eines sich rasant entwickelnden Kommunikationsmediums, die nicht sofort wieder veralten; sie zeichnet die dauerhaften Z?ge dieses schon seit ?ber vierzig Jahren bestehenden Netzwerks nach: Denn nur aus der Geschichte des Internet lassen sich wese...
2,200円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Theorien des Internet zur Einf?hrung【電子書籍】[ Martin Warnke ]
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個...
3,179円
 税込 送料別 カードOK  Glomarket 洋書 Paperback, Primary composition notebook: Experiment Back to school pattern Story Paper to write in for students 120 pages (8.5 x 11 Inch).
<p><strong>Volver a dormir bien es posible.</strong></p> <p>La mitad de los adultos sufre insomnio. Muchos recurren a pastillas. Otros prueban consejos que no funcionan. Pero casi nadie entiende qu? est? pasando realmente en su mente.</p> <p>En este libro revolucionario, Rafael Santandreu revela que la mayor?a de los casos de insomnio son psicol?gicos y tienen soluci?n definitiva. En sus p?ginas aprender?s c?mo <strong>romper el c?rculo vicioso del miedo</strong>, c?mo <strong>reprogramar tu cerebro</strong> para dormir profundamente y c?mo <strong>calmar la mente</strong> para que la noche vuelva a ser <strong>paz y descanso</strong>.</p> <p><strong>?En qu? se diferencia este libro de otros libros sobre insomnio?</strong></p> <p><strong>・ Enfoque innovador</strong>: con la psicolog?a cognitiva como base, este libro describe diferentes trastornos de sue?o y aporta soluciones espec?ficas pata tratarlos.</p> <p><strong>・ Alternativa a los f?rmacos</strong>: este es un m?todo alternativo que funciona, frente a la dependencia de las pastillas o medicamentos para dormir.</p> <p><strong>・ Resultados desde la primera noche</strong>: un m?todo pr?ctico y aplicable de forma inmediata para todas las personas con este problema.</p> <p><strong>・ Avalado cient?ficamente</strong>: una base cient?fica que nace de la terapia cognitivo-conductual, recomendada como primera l?nea de tratamiento.</p> <p><strong>・ Transformaci?n m?s all? del sue?o</strong>: un libro que no solo mejora el descanso y mitiga el insomnio, sino que redefine la gesti?n emocional y la fortaleza mental.</p> <p><strong>La terapia pr?ctica y definitiva contra el insomnio que podr?s aplicar de forma inmediata.</strong><br /> <strong>Cient?fica, comprobada y sin f?rmacos.</strong></p> <p><strong>La opini?n de los profesionales:</strong><br /> ≪Receto sus libros como parte del tratamiento integral que necesitan mis pacientes≫.<br /> Dra. Carima Belleyo, cardi?loga</p> <p>≪M?todos comprobados y realmente eficaces≫.<br /> Ana Cerezales, m?dico internista</p> <p>≪La mejor psicolog?a que conozco, da lugar a transformaciones impresionantes≫.<br /> Esther Garrido, anestesi?loga</p> <p>≪Recomiendo decididamente esta forma de terapia. Herramientas comprobadas para mejorar la salud mental≫.<br /> Mar?a Jes?s Almod?var, m?dico del trabajo</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
1,300円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Dormir cuando no puedes dormir El m?todo comprobado para superar el insomnio【電子書籍】[ Rafael Santandreu ]
<p>countries in this region have been particularly limited (for an exception to this, see Petmesidou & Papatheodorou, 2006). The underlying assumption in this volume is that despite the diversity of welfare states bordering the Mediterranean Sea, some interesting commonalities are shared by these nati...
12,154円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Children, Gender and Families in Mediterranean Welfare States【電子書籍】
<p><em>Human-in-the-Loop Simulations</em> is a compilation of articles from experts in the design, development, and use of human-in-the-loop simulations.</p> <p>The first section of the handbook consists of papers on fundamental concepts in human-in-the-loop simulations, such as object-oriented simulation d...
12,154円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Human-in-the-Loop Simulations Methods and Practice【電子書籍】
<p>This theses reports on an experimental search for an exotic hadron, Θ+(1540) pentaquark, which is a genuine exotic hadron with a five-quark system of uuddsbar. The results of this book support that the existence of Θ+ was strongly constrained.</p> <p>The Θ+ pentaquark was searched for via the π- p ...
12,154円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Search for the Pentaquark Θ+ via the πーp → KーX Reaction at J-PARC【電子書籍】[ Manabu Moritsu ]
<p>This book provides an excellent introduction into polysaccharide-based supercapacitors. It includes fundamental knowledge on supercaps as well as an overview of currently available approaches reported in the literature. Written by an international team of leading academics, this brief is aimed at a...
6,076円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Polysaccharide Based Supercapacitors【電子書籍】[ Soon Yee Liew ]
<p>On the Origin of Species, published on 24 November 1859, is a work of scientific literature by Charles Darwin which is considered to be the foundation of evolutionary biology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページ...
129円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア On the Origin of Species【電子書籍】[ Charles Darwin ]
<p>In der Pflege betagter Menschen werden Pflegende teilweise mit Bewohnerinnen und Bewohnern konfrontiert, die Verhaltensauff?lligkeiten aufweisen. Praxisbezogen und leicht verst?ndlich zeigt das Buch M?glichkeiten auf, wie diesen unkompliziert und rasch geholfen werden kann. Das bringt Entlastung f?r die Betroffenen und deren Umfeld. Das aus zw?lf Schwerpunkten bestehende Konzept wird w?hrend der Pflege und dem allt?glichen Umgang mit betagten Menschen umgesetzt. Dabei werden weniger die Verhaltensauff?lligkeiten beachtet, sondern mehr die Bed?rfnisse, die sich hinter diesen verstecken. Das Konzept wurde in der Pflege betagter Menschen entwickelt und hat sich in der Praxis vielfach bew?hrt.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
3,000円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Pflege von betagten Menschen mit Verhaltensauff?lligkeiten【電子書籍】[ Theres Bausch-Walther ]
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個...
5,714円
 税込 送料別 カードOK  Glomarket 洋書 Basic Books paperback Book, The Lifebox, the Seashell, and the Soul: What Gnarly Computation Taught Me About Ultimate Reality, the Meaning of Life, and How to Be Happy
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、全てご注文者自身の「個人使用・個人消費(日本に居住する者に寄贈される物で、当該寄贈を受ける者の個人的な使用に供される場合を含みます。)」が前 提となります。第三者への譲渡・転売が法令で禁止されるもの(医薬品、医薬部外品、化粧品等を含みますが、これに限られません。)もございますのでご注意下さい。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文
12,845円
 税込 送料別 カードOK  Glomarket 洋書 Princeton University Press paperback Book, The Great Famine
<p>The world is awash in chemicals created by fellow citizens, but we know little to nothing about them. Understanding whether even the most prevalent ones are toxic would take decades. Many people have tragically suffered serious diseases and premature death, including children during development. Wh...
4,004円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Tragic Failures How and Why We are Harmed by Toxic Chemicals【電子書籍】[ Carl F. Cranor ]
<p>Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book ar...
13,369円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Lung Cancer Metastasis Novel Biological Mechanisms and Impact on Clinical Practice【電子書籍】
<p>Neugier treibt uns Menschen an und hat gro?artige Expeditionen ?ber das Eis, in tiefe Ozeane und bis zum Mond erm?glicht.<br /> Die <em>Fram2</em>-Mission war eine solche Expedition, bei welcher zum ersten Mal ein Raumschiff mit menschlicher Besatzung ?ber beide Polarregionen der Erde reiste.</p> <p>Mein Nam...
2,057円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Ein (bisschen) Weltraum f?r Alle Gedanken einer Astronautin zu Expeditionen, Robotern und Zukunftsvisionen【電子書籍】[ Rabea Rogge ]
<p><strong>Ethnomedicine: Ancestral Legacy and Use of Medicinal Plants</strong> is a book that explores the deep connection between humanity and medicinal plants, blending ancestral wisdom with modern scientific perspectives. Written by experts from four continents, it presents diverse healing tradition...
30,287円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Ethnomedicine Ancestral Legacy and Use of Medicinal Plants【電子書籍】[ Jos? L. Mart?nez ]
<p>This insightful book explores the impact of internet-based technologies on second language acquisition, focusing on informal learning. It traces the evolution of informal learning, emphasizing the crucial role of input, interaction, and output in acquiring English as a second language. The book ana...
7,860円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Informal Language Learning Expanding the English Learning Horizons Beyond the Classroom【電子書籍】[ Marian Amengual-Pizarro ]
<p>En un mundo donde la ciencia y la espiritualidad a menudo parecen ser antit?ticas, Todo es Energ?a se erige como un puente fascinante entre estas dos esferas, llevando al lector en un viaje iluminador que revela la profunda conexi?n entre los minerales, las emociones y el bienestar humano. Este lib...
1,300円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Todo es energ?a. Un despertar con los minerales【電子書籍】[ GUSTAVO ROJAS ]
<p>“Bob Zubrin really, nearly alone, changed our thinking on this issue.”</p> <p>ーCarl Sagan, <em>The Denver Post</em></p> <p><strong>If you ever daydream about space travel and human space flightーor hope to one day rove the Red Planet alongside <em>Curiosity</em>ーthen MARS DIRECT will teach you how we can get ...
1,100円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Mars Direct Space Exploration, the Red Planet, and the Human Future: A Special from Tarcher/Penguin【電子書籍】[ Robert Zubrin ]
<p>Enormous in scope, this book presents in comprehensive and logical form the sum of our national knowledge about renewable energy resources. It deals with these resources in terms of opportunities and dangers, in terms of current availability and possible expansion, in terms of how natural resources...
8,917円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Renewable Natural Resources A Management Handbook For The Eighties【電子書籍】[ Dennis Little ]
<p><strong>Combining bold graphics with easy-to-understand text, <em>Simply Chemistry</em> is the perfect introduction for those who are short of time but hungry for knowledge.</strong></p> <p>This book covers the core concepts of chemistry in a fresh and accessible way ? from the structure of an atom and the...
2,387円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Simply Chemistry Facts Made Fast【電子書籍】[ DK ]
<p>Whether you're preparing for a course exam or for the physiology portion of the USMLE Step 1, Guyton and Hall Physiology Review, 5th Edition, is your go-to resource for effective, efficient study. This practical review tool is an ideal companion to the world's foremost physiology textbook, offering...
5,232円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Guyton & Hall Physiology Review - E-Book Guyton & Hall Physiology Review - E-Book【電子書籍】[ John E. Hall ]
<p>In his comprehensive work, "Supplement to the Catalogue of Seals and Whales in the British Museum," John Edward Gray meticulously expands upon the extant collections of marine mammals, providing an analytical yet accessible overview of their classifications, characteristics, and ecological signific...
150円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Supplement to the catalogue of seals and whales in the British Museum Exploring the Marine World: A Taxonomic Supplement【電子書籍】[ John Edward Gray ]
<p>A revealing overview of the issue of drug addiction, including the treatment and the active role of the family unit. Discover the influence of drugs over time, in an era in which everything is fast-paced and immediate. The perspective of Eduardo Kalina, a prestigious psychiatrist and addictions spe...
880円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Chemical Dependency Understanding a problem that affects the whole family【電子書籍】[ Dr. Eduardo Kalina ]
<p>Das "neuartige" Long-Covid-Syndrom und das Chronic-Fatigue-Syndrom (ME/CFS) sind zwei Namen f?r ein und dieselbe Erkrankung. Dr. med. Bernhard Dickreiter zeigt erstmalig die biologischen Ver?nderungen auf Zellebene auf: Was passiert bei dieser Erkrankung in den Zellen, in der Zellumgebung und in de...
2,600円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Raus aus der chronischen Ersch?pfung Long Covid und das Chronic Fatigue Syndrom verstehen und lindern【電子書籍】[ Bernhard Dickreiter ]
<p>This book introduces a multidimensional system that evaluates quality of life in China by pursuing a quantitative and analytical approach. A host of factors, including economic conditions and individual wellbeing, can affect people’s satisfaction with their lives. In addition to GDP-associated indi...
18,231円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア The Quality of Life in Contemporary China 【電子書籍】
<p>Drugs provide temporary relief from diseases but their regular intake causes side effects in the body. As per concepts of naturopathy, if you eat natural foods, you will never need drugs. So adopt healthy eating habits to get a fit life ahead. The keyword to good health is detoxification of the ent...
1,077円
 税込 送料込 カードOK  楽天Kobo電子書籍ストア Fruit Therapy Detox Your Body for Naturally Combatting Ailments【電子書籍】[ Vikas Khatri ]
データー更新:2026/04/21 17:36:07


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